LRP1 Gene – Abdominal Aortic Aneurysm (AAA) Discovery And Do You Have AAA+Dyslipidemia?


Hi folks,

'statin pathway' diagram with LRP1

So-called statin pathway, in which you can see LRP1 having a central location. Click on diagram for detail, and use back browser button to return to post. From:

Great news this week with respect to the possible underlying mechanism of abdominal aortic aneurysm (AAA), a link between AAA and the gene LRP1. The authors said, “Through this research we have identified a gene that is associated with AAA and the further investigation of the function of this gene in relation to AAA may help us understand more about the disease and how to treat it without resorting to operations.

How is that for great news? Interestingly, this gene lies in a network associated with lipid metabolism, and I have in addition to AAA a severe form of dyslipidemia that has only consistently responded to intense exercise, and I mean intense exercise. Better than statins. Better than fish oil.

Any other AAA (or aortic dissection) people out there with dyslipidemia?

-k Your Medical Mind


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Disclaimer: As a veterinarian, I do not provide medical advice for human animals. If you undertake or modify an exercise program, consult your medical advisors before doing so. Undertaking activities pursued by the author does not mean that he endorses your undertaking such activities, which is clearly your decision and responsibility. Be careful and sensible, please.